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A Novel Highly Stereoselective Synthesis of 2,3-Disubstituted 3H-Quinazoline-4-one Derivatives.

โœ Scribed by Paul Zhichkin; Edward Kesicki; Jennifer Treiberg; Lisa Bourdon; Matthew Ronsheim; Hua Chee Ooi; Stephen White; Angela Judkins; David Fairfax

Publisher
John Wiley and Sons
Year
2007
Weight
39 KB
Volume
38
Category
Article
ISSN
0931-7597

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โœฆ Synopsis

Abstract

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๐Ÿ“œ SIMILAR VOLUMES

ChemInform Abstract: Stereoselective Syn
ChemInform Abstract: Stereoselective Synthesis of a 2,3-Disubstituted 5-Pyrrolidinone Derivative of Quinazolin-4(3H)-one.
โœ M. SZABO; J. KOEKOESI; A. KOVACS; Z. BOECSKEI; I. HERMECZ ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 29 KB ๐Ÿ‘ 1 views

Stereoselective Synthesis of a 2,3-Disubstituted 5-Pyrrolidinone Derivative of Quinazolin-4(3H)-one. -Thermal acylation of the quinazolinone (III) with ethyl acetoacetate and subsequent thermal cyclization of the intermediate acetoacetamide results in selective formation of the title compound (V),