A Novel Family of S-Nitrosothiols: Chemical Synthesis and Biological Actions
β Scribed by Haitham H. Al-Sa'doni; Imran Y. Khan; Lucilla Poston; Ian Fisher; Albert Ferro
- Book ID
- 115642095
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 140 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1089-8603
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The molecular structure of a stable S-nitrosothiol bearing a novel trityl-type steric protection group was established by X-ray crystallographic analysis together with that of the corresponding S-nitrothiol. It was found that the S-nitrosothiol exists as a mixture of the syn and anti isomers with re
The endotoxic principle of lipopolysaccharides (LPS) is localized in their lipid A component. Biological effects of LPS on, for instance, body temperature, blood pressure, and blood picture, are also induced by free lipid A. In contrast to the great variability of the 0-specific chains, the chemical