𝔖 Bobbio Scriptorium
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A Novel Entry to Corticoids

✍ Scribed by Dr. Ulrich Kerb; Manfred Stahnke; Dr. Paul-Eberhard Schulze; Prof. Dr. Rudolf Wiechert

Publisher
John Wiley and Sons
Year
1981
Tongue
English
Weight
442 KB
Volume
20
Category
Article
ISSN
0044-8249

No coin nor oath required. For personal study only.

✦ Synopsis

Compounds of type ( I ) and ( ) are key substances for the synthesis of highly active corticoids'll such as dexamethasone, betamethasone and triamcinolone. The usual methods for their technical production are based on microbiological hydroxylation at C,, and dehydration with cleavage of the 11-and l7a-hydroxy groups.

(a), R = H; (h), R = Acyl

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