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A novel dicationic polyamide ligand binds in the DNA minor groove as a dimer

✍ Scribed by Wentao Zhang; Yuqin Dai; Uli Schmitz; Thomas W. Bruice

Book ID
117103603
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
367 KB
Volume
509
Category
Article
ISSN
0014-5793

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πŸ“œ SIMILAR VOLUMES

Simultaneous binding of a polyamide dime
Simultaneous binding of a polyamide dimer and an oligonucleotide in the minor and major grooves of DNA
✍ Michelle E. Parks; Peter B. Dervan πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 645 KB

The effect of the polyamide ImPyPy-Dp (Im = N-methylimidazole-2-carboxamide, Py = N-methylpyrrole-2-carboxamide, and Dp = dimethylaminopropylamide), which binds as an antiparallel dimer in the Watson-Crick minor groove, on pyrimidine. purine.pyrimidine triple helix stability was investigated. A DNA