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A novel cyclin encoded by a bcl1-linked candidate oncogene

✍ Scribed by Motokura, Toru; Bloom, Theodora; Kim, Hyung Goo; Jüppner., Harald; Ruderman, Joan V.; Kronenberg, Henry M.; Arnold, Andrew

Book ID
109773147
Publisher
Nature Publishing Group
Year
1991
Tongue
English
Weight
559 KB
Volume
350
Category
Article
ISSN
0028-0836

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The cyclin D1/PRAD1 oncogene, a key regulator of the G 1 phase of the cell cycle, has been incriminated in the pathogenesis of human neoplasia. Cyclin D1 was also demonstrated to be identical to the long-sought bcl-1 oncogene in B-cell malignancies with the t(11;14)(q13;q32) translocation. We report