A novel approach to structural analysis of oligonucleotides
β Scribed by E.D. Sverdlov; G.S. Monastyrskaya; E.I. Budowsky; M.A. Grachev
- Book ID
- 115903183
- Publisher
- Elsevier Science
- Year
- 1972
- Tongue
- English
- Weight
- 440 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0014-5793
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π SIMILAR VOLUMES
## Abstract A new process for preparing oligonucleotide arrays is described that uses surface grafting chemistry which is fundamentally different from the electrostatic adsorption and organic covalent binding methods normally employed. Solid supports are modified with a mixed organic/inorganic zirc
A fundamentally novel approach to the synthesis of oligocyclopropane structural units based on the iterative formation and trapping of homo-allyl cationic intermediates has been accomplished. This methodology provides practical access to the diastereomieally related trans-syn-trans and trans-ant/-tr