Oxidation of natural targets by dioxiran
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Antonia Detomaso; Ruggero Curci
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Article
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2001
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Elsevier Science
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French
⚖ 80 KB
An efficient approach to the synthesis of N-hydroxyamino acids in high enantiomeric excess is described; this involves the high-yielding selective N-hydroxylation of N-Boc protected primary amino acid esters with methyl(trifluoromethyl)dioxirane under mild conditions.