A new α2HS-glycoprotein allele (AHS*5⋆) in two Japanese families
✍ Scribed by K. Umetsu; S. Kashimura; N. Ikeda; T. Suzuki
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 187 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0340-6717
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✦ Synopsis
Serum specimens of two unrelated Japanese males had a new variant of the azHS-glycoprotein phenotypes. They had unusual bands designated AHS 5. Family studies indicated that the new variant phenotypes were determined by a new allele, AHS*5, in combination with a common allele AHS*I or AHS*2, and that the new allele had an autosomal codominant inheritance with other AHS alleles. The frequency of the new a2HS-glycoprotein allele, AHS*5, is 0.0005.
Up to the present day, we have investigated blood samples from 2050 unrelated healthy individuals for a2HS polymorphism. Recently, we observed new variant a2HS phenotypes in two samples.
The following report describes the finding of new c~2HS phenotypes and the fifth allele, AHS*5, in family studies.
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