A new translocation in Burkitt's tumor cells
✍ Scribed by R. Berger; A. Bernheim; H. -J. Weh; G. Flandrin; Marie-Thérèse Daniel; J. -C. Brouet; N. Colbert
- Book ID
- 104706431
- Publisher
- Springer
- Year
- 1979
- Tongue
- English
- Weight
- 167 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0340-6717
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✦ Synopsis
A t(8;22)(q24;q11) translocation was found in blood, bone marrow, and ascites cells from a European Burkitt's lymphoma. Cell surface markers were identified as monoclonal IgG. The relationship between these two unusual findings is questionable in this cytologically typical Burkitt's lymphoma.
📜 SIMILAR VOLUMES
The human MLV14 locus, located 20 kilobases 3' of MYC, is rearranged in two Burkitt's lymphoma cell lines with either a t(28)(p12;q24) or t(822)(q24;q I I). Alterations of MLV14 may have prognostic significance in some types of 6-cell malignancies.
## Abstract Two established North American Burkitt lymphoma cell lines were studied by chromosomal banding techniques. The SU‐AmB‐1 line previously shown to be negative for the Epstein‐Barr virus (EBV) was found to have, among other changes, a translocation from the long arm (q) of chromosome 8 ont