The solid phase synthesis of unsymmetric
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Philip B Cox; Vincent M Loh Jr.; Claude Monteils; Anthony D Baxter; E.Andrew Boy
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Article
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2001
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Elsevier Science
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French
β 110 KB
This letter describes a method for the synthesis of unsymmetrical phosphinic acids by the phosphinylation of a resin-bound aldehyde and subsequent 'P' alkylation. This synthetic transformation is very difficult to perform as selectively in solution and therefore further exemplifies the powerful natu