A new synthesis of staurosporinone
β Scribed by Egle M. Beccalli; Maria Luisa Gelmi; Alessandro Marchesini
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 419 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0040-4020
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β¦ Synopsis
A new six steps synthesis of staurosporinone 4, starting from 3-cyano-3-(1H-indol-3-yl)-2-oxo-propionic acid ethyl ester 5, is reported.
π SIMILAR VOLUMES
A new, simple, high-yield synthesis of the indolo[2,3-a]carbazole alkaloid staurosporinone is described.
In recent years several approaches to hydroazulenes involving efficient and ingenious synthetic designs have been developed. 1 We report here a new route to 6-methyl-bicyclo(5,3,O)-deca-l,6-dien-3-one (4).2 Treatment of the bicyclic enedione (1) with dimethyloxosulfoniu methylide (DMSM)3 in dimet%l
Hypoglycin A, (III), a new aminoacid with marked hypoglycasmic properties was isolsted by Hassal' from unripe ackee fruit (Blighia sapida) and subsequently synthesised in six stages from 2-bromo-propene by Carbon, Martin and Svett2. In our three stage synthesis l-bromo--buta-2,3-diene3 was condensed