A new synthesis of N-alkyl pyrazolidine-3,5-diones and tetrahydropyridazine-3,6-diones
✍ Scribed by Bertrand Le Bourdonnec; Emmanuelle Meulon; Saïd Yous; Raymond Houssin; Jean-Pierre Hénichart
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2000
- Tongue
- English
- Weight
- 335 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
Abstract
N‐alkyl pyrazolidine‐3,5‐diones and tetrahydropyridazine‐3,6‐diones have been synthesized by a new method in a three‐step sequence from dialkyl malonates or succinates respectively.
📜 SIMILAR VOLUMES
To our knowledge only one unsubstituted heteroalicyclic vicinal diketone I has been prepared, and it was made by a wthod unique to that structure (1) . While 11 is known (2.3) and is
## Abstract The dialkylpiperazines are prepared from α‐amino acid ester hydrochlorides in three steps.
Synthesis and Antiaggregating Activity of 3-Aminopiperidine-2,6dione and 3-Aminopyrrolidine-2,5-dione Derivatives. -Several substituted 3-aminopiperidine-2,6-diones as well as their pyrrolidine analogues [cf. (VI), (VIII)] are prepared via reaction of anhydrides derived from N-Boc-protected 2-amino