✦ LIBER ✦

A new synthesis of alkyl 1-alkyl-2-methylpyrrole-3-carboxylates by ring transformation of 2-chloro-2-acetimidoylbutyrolactones

✍ Scribed by Bart Kesteleyn; Erick Rosas Alonso; Christian Stevens; Yves Dejaegher; Maria Peristeropoulou; Tuyen Nguyen Van; Oleg Kulinkovich; Norbert De Kimpe

Publisher: Elsevier Science
Year: 1999
Tongue: French
Weight: 851 KB
Volume: 55
Category: Article
ISSN: 0040-4020
DOI: 10.1016/s0040-4020(99)00108-8

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✦ Synopsis

Reaction of 2-chloro-2-acetimidoylbutyrolactones with sodium methoxide or sodium ethoxide in the corresponding alcohol provides a facile one-step synthesis of methyl or ethyl l-alkyl-2methylpyrrole-3-carboxylates from readily available starting materials.

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