A New, Stereospecific Olefin Synthesis from 1,2-Diols
β Scribed by Corey, E. J.; Winter, Roland A. E.
- Book ID
- 121076788
- Publisher
- American Chemical Society
- Year
- 1963
- Tongue
- English
- Weight
- 283 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0002-7863
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A total synthesis of (+)-spat01 (1) was achieved which depends upon a novel stereospecific transformation of trans-2,3-epoxy-1,4-diols to generate the sensitive allylic vicinal cisdiepoxide in 1. Spat01 (l), a structurally and functionally complex minor metabolite produced by a tropical