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A new solid-phase synthesis of porcine vasoactive intestinal peptide using Nα-9-fluorenylmethyloxycarbonyl amino acids

✍ Scribed by R. Colombo


Publisher
Springer
Year
1982
Tongue
English
Weight
312 KB
Volume
38
Category
Article
ISSN
1420-682X

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Peptide synthesis by a combination of so
✍ M. Mergler; R. Nyfeler; J. Gosteli; R. Tanner 📂 Article 📅 1989 🏛 Elsevier Science 🌐 French ⚖ 175 KB

The cesium salts of N -9-fluorenylmethyloxycarbonyl (Fmoc) amino acids couple smoothly to new chloro derivatives of alkoxy benryl alcohol resins. While high loading is attained under mild reaction conditions racemization can be suppressed even with Cys and His derivatives.