A new simple preparation of d-alloisoleucine suitable for large-scale manufacture

✍ Scribed by Hirofumi Noda; Kenichi Sakai; Hisamichi Murakami

• Book ID: 104359534
• Publisher: Elsevier Science
• Year: 2002
• Tongue: English
• Weight: 91 KB
• Volume: 13
• Category: Article
• ISSN: 0957-4166
• DOI: 10.1016/s0957-4166(02)00719-x

✦ Synopsis

D-Alloisoleucine (D-aIle) was obtained by the resolution of the epimer mixture of L-isoleucine (L-Ile) and D-aIle, which was formed by epimerization of L-Ile, with a resolving agent such as (2S,3S)-dibenzoyltartaric acid ((2S,3S)-DBTA) or (2S,3S)-di-4-toluoyl tartaric acid ((2S,3S)-DTTA).