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A new, selective method for conversion of alcohols to vicinal fluorohydrins

✍ Scribed by Stavber, Stojan; Zupan, Marko


Book ID
115523210
Publisher
The Royal Society of Chemistry
Year
1994
Tongue
English
Weight
278 KB
Volume
2
Category
Article
ISSN
0022-4936

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A new, highly efficient method for the c
✍ R.P. Volante πŸ“‚ Article πŸ“… 1981 πŸ› Elsevier Science 🌐 French βš– 176 KB

Various alcohols were converted to their corresponding thiolacetates by treatment with triphenylphosphine and diisopropyl azodicarboxylate in the presence of thiolacetlc acid. The overall conversion was both highly efficient (89-99X yields) and stereoselective (99.5% inversion).