A new route to chiral imidazolidine salts and its application in organometallic synthesis
✍ Scribed by Sandra C. Zinner; Wolfgang A. Herrmann; Fritz E. Kühn
- Book ID
- 108284354
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 187 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0957-4166
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📜 SIMILAR VOLUMES
The first chiral triaminosulfonium salt, tris((S,S)-3,4-diphenylpyrrolidino)sulfonium difluorotriphenylstannate, catalyzes trifluoromethylation of benzaldehyde with (trifluoromethyl)trimethylsilane to give the corresponding optically active alcohol with 52% ee.
Several chiral imidazolidine disulfides 4a-d derived from L-cystine have been synthesized. These ligands have been applied as chiral catalysts in the asymmetric addition of diethylzinc to aldehydes. The best results were obtained by employing 5 mol% of imidazolidine disulfide 4a, and chiral secondar