𝔖 Bobbio Scriptorium
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New Synthetic Route to 2-Pyridones and Its Application toward the Synthesis of (±)-Ipalbidine †

✍ Scribed by Sheehan, Scott M.; Padwa, Albert


Book ID
125511233
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
93 KB
Volume
62
Category
Article
ISSN
0022-3263

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New synthetic route towards 2,2-dimethyl
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## Abstract magnified image Trifluoromethansufonic acid (TFA) was found a proper reagent for regioselectively ring closure of resorcinol to afford 7‐hydroxy‐2,2‐dimethyl‐2,3‐dihydrochromen‐4‐one **3**. The propargylation of **3** gave rise to 2,2‐dimethyl‐7‐(2‐methylbut‐3‐yn‐2‐yloxy)‐2,3‐dihydroch