A new protecting-group strategy for indoles
β Scribed by Katherine E Bashford; Anthony L Cooper; Peter D Kane; Christopher J Moody
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 118 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
The 2-phenylsulfonylethyl group is a useful alkyl protecting group for nitrogen during indole synthesis; it is readily removed from the indole nitrogen under basic conditions.
π SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
The diethylisopropylsilyl (DEIPS) group which is a new protective group for alcohols has been first characterized. DEIPS group can be distinguished from t-butyldimethylsilyl, triethylsilyl, tetrahydropyranyl groups and 2-deoxy glycoside with high selectivity in removing under mild acidic condition,
A new alkyne protecting group, trispyrazolylborateplatinum(methyl) (TPM), that can tolerate various reaction conditions and is particularly useful for electron-deficient acetylenes allows for synthetic manipulations of polyfunctional acetylenes. This protecting group withstands a variety of reaction