The diethylisopropylsilyl group: A new protecting group for alcohols

✍ Scribed by Kazunobu Toshima; Satsuki Mukaiyama; Mitsuhiro Kinoshita; Kuniaki Tatsuta

• Publisher: Elsevier Science
• Year: 1989
• Tongue: French
• Weight: 167 KB
• Volume: 30
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)93909-7

✦ Synopsis

The diethylisopropylsilyl (DEIPS) group which is a new protective group for alcohols has been first characterized. DEIPS group can be distinguished from t-butyldimethylsilyl, triethylsilyl, tetrahydropyranyl groups and 2-deoxy glycoside with high selectivity in removing under mild acidic condition, although DEIPS group has high stability to many useful organic synthetic reaction conditions.