During the course of various synthetic projects under study in these Laboratories we have had occasion to devise and apply a number of new methods for the protection of hydroxyl' , carbony and la&one' functions. 4 We now wish to report some recent results on the protection of aldehydes and ketones
A new protecting group for the sulfhydryl function of cysteine
β Scribed by Schroll, Alayne L.; Barany, George
- Book ID
- 121404548
- Publisher
- American Chemical Society
- Year
- 1989
- Tongue
- English
- Weight
- 571 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
The diethylisopropylsilyl (DEIPS) group which is a new protective group for alcohols has been first characterized. DEIPS group can be distinguished from t-butyldimethylsilyl, triethylsilyl, tetrahydropyranyl groups and 2-deoxy glycoside with high selectivity in removing under mild acidic condition,
2-(Terf-butytdiphenylsiiybxymethyl)benzoyl chbrkfe (SiOMB-Cl) reads with the per-0-trimethylsilylated dnucleoskbs C,G and A to give, after removal of the Si(Me), groups and 5'-O-pmtectbn with 4,4'dimethoxytrityl chbride (DMT-Cl), the corresponding NSiOMB-5'-O-DMT derivates, the SiOMB groups of which