4-(3-Hydroxy-4-methylpentyl)phenylacetic
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Katri Rosenthal; Mikael Erlandsson; Anders UndΓ©n
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Article
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1999
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Elsevier Science
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French
β 200 KB
The anchoring the first amino acid in Boc chemistry to a 4-(3-hydroxy-4methylpentyl)phenylacetic acid linker is described and compared to the conventional Pam resin. The peptidyl-4-(4-methyl-3-pentoxy)phenylacetamide linkage is slightly more stable to TFA than the Pam linker but in contrast to the P