A New Precatalyst for the Suzuki Reaction — A Pyridyl-bridged Dinuclear Palladium Complex as a Source of Mono-ligated Palladium(0).
✍ Scribed by Andrew Beeby; Syliva Bettington; Ian J. S. Fairlamb; Andres E. Goeta; Anant R. Kapdi; Elina H. Niemelae; Amber L. Thompson
- Book ID
- 101967216
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 20 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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Boronic acids which quickly deboronate under basic conditions, such as polyfluorophenylboronic acid and fivemembered 2-heteroaromatic boronic acids, are especially challenging coupling partners for Suzuki-Miyaura reactions. Nevertheless, being able to use these substrates is highly desirable for a n
## Abstract magnified image The synthesis of 2‐acetyl‐6‐(1‐naphthyl)‐pyridine oxime ligand from 2,6‐dibromopyridine and 1‐bromo‐naphthalene is described, and the new palladium(II) complex used as a Pd(0) precatalyst in the Suzuki cross‐coupling reaction was studied. The results showed that the nov
## Abstract Polyfluorophenylboronic acid and five‐membered heteroaromatic boronic acids are used as coupling partners for Suzuki—Miyaura reactions in the presence of a newly developed precatalyst.