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A new photoaffinity probe, 4-amino-2-[4-(4-azidocinnamoyl)piperazino]-6,7-dimethoxyquinazoline, for α1-adrenoceptors

✍ Scribed by John W. Kusiak; Zoltán Szurmai; Josef Pitha


Book ID
115880328
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
715 KB
Volume
123
Category
Article
ISSN
0014-2999

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✍ Paola Rossi; Fulvia Felluga; Paolo Scrimin 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 221 KB

The title amino acid was obtained by regiospecific ring-opening reaction of Bocdiprotocted 1,4,7-tfiazacyolononane with (S)-2-benzyloxTcarbonylamino-~3-1actone ~80% isolated yield) followed by deprotection. It strongly binds transition metal ions like Zn and Cu n and can be incorporated in peptide s