A New Palladium-Catalyzed Addition: A Mild Method for the Synthesis of Coumarins
β Scribed by Trost, Barry M.; Toste, F. Dean
- Book ID
- 120809053
- Publisher
- American Chemical Society
- Year
- 1996
- Tongue
- English
- Weight
- 128 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
## Abstract In contrast to BrΓΈnsted and other Lewis acids ClTi(O__i__Pr)~3~ is especially suited to catalyze the formation of aminoβsubstituted coumarins from aminophenols and functionalized Ξ²βoxo esters in a Pechmann condensation. This straightforward protocol allows the synthesis of fluorescence
## Abstract For Abstract see ChemInform Abstract in Full Text.
A new method for the synthesis of amidines is presented using N-acetylcysteine as a catalyst. The key advantage of this new method is that it is compatible with a large number of functional groups. It allows the synthesis of amidines in complex molecules containing acid-labile groups, base-labile ce