𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A new method for the enzymic synthesis of nucleosides using purine nucleoside phosphorylase

✍ Scribed by Hennen, William J.; Wong, Chi Huey

Book ID
118042385
Publisher
American Chemical Society
Year
1989
Tongue
English
Weight
540 KB
Volume
54
Category
Article
ISSN
0022-3263

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

A new ultramicrochemical assay for purin
A new ultramicrochemical assay for purine nucleoside phosphorylase
✍ M.P. Uitendaal; C.H.M.M. de Bruyn; T.L. Oei; P. HΓΆsli; C. Griscelli πŸ“‚ Article πŸ“… 1978 πŸ› Elsevier Science 🌐 English βš– 375 KB

An ultramicrochemical method using radioactive substrates has been developed for the quantitation of purine nucleoside phosphorylase (NP) activity in single cells. NP activity can reproducibly be measured in both directions of the enzyme reaction. A quantitative relationship between the number of ce

A new isotopic assay for purine nucleosi
A new isotopic assay for purine nucleoside phosphorylase
✍ Chi-Hsiung Chang; L.Lee Benneett Jr.; R.W. Brockman πŸ“‚ Article πŸ“… 1989 πŸ› Elsevier Science 🌐 English βš– 405 KB

We have developed a new assay for purine nucleoside phosphorylase which is based on the release of tritium when [2-3H]inosine is used as the substrate and the reaction is coupled with xanthine oxidase. After the reaction is terminated, residual [2-3H]inosine is adsorbed on charcoal and the supernata

Synthesis of deuterated-BCX-1777, a pote
Synthesis of deuterated-BCX-1777, a potent inhibitor of purine nucleoside phosphorylase
✍ Hollis S. Kezar III; Tracy L. Hutchison; Peter C. Tyler; Philip E. Morris Jr. πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 French βš– 112 KB

## Abstract BCX‐1777, a novel inhibitor of the enzyme purine nucleoside phosphorylase, mimics the charged ribosyl oxocarbenium ion formed during the transition state of the enzyme‐catalyzed Cο£ΏN bond cleavage of nucleosides. BCX‐1777 is a slow‐onset, tight‐binding inhibitor with a __K__~__i__~^\*^ o