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A New Locus for Autosomal Dominant Pure Spastic Paraplegia, on Chromosome 2q24-q34

✍ Scribed by Bertrand Fontaine; Claire-Sophie Davoine; Alexandra Dürr; Caroline Paternotte; Imed Feki; Jean Weissenbach; Jamilé Hazan; Alexis Brice


Book ID
117853175
Publisher
American Society of Human Genetics
Year
2000
Tongue
English
Weight
682 KB
Volume
66
Category
Article
ISSN
0002-9297

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Novel locus for autosomal dominant pure
✍ Enza Maria Valente; Francesco Brancati; Viviana Caputo; Enrico Bertini; Clarice 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 93 KB 👁 2 views

Hereditary spastic paraplegia is a clinically and genetically heterogeneous disorder characterized by progressive spasticity of the lower limbs. Seven loci for autosomal dominant pure hereditary spastic paraplegia (ADPHSP) have already been mapped on chromosomes 14q, 2p, 15q, 8p, 12q, 19q, and 2q. W