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A Locus for Autosomal Dominant “Pure” Hereditary Spastic Paraplegia Maps to Chromosome 19q13

✍ Scribed by E. Reid; A.M. Dearlove; O. Osborn; M.T. Rogers; D.C. Rubinsztein


Book ID
117853181
Publisher
American Society of Human Genetics
Year
2000
Tongue
English
Weight
550 KB
Volume
66
Category
Article
ISSN
0002-9297

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Hereditary spastic paraplegia is a clinically and genetically heterogeneous disorder characterized by progressive spasticity of the lower limbs. Seven loci for autosomal dominant pure hereditary spastic paraplegia (ADPHSP) have already been mapped on chromosomes 14q, 2p, 15q, 8p, 12q, 19q, and 2q. W