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A new HILIC-MS/MS method for the simultaneous analysis of carbidopa, levodopa, and its metabolites in human plasma

✍ Scribed by Vilhena, Raquel de Oliveira (author);Pontes, Flávia Lada Degaut (author);Marson, Breno Maurício (author);Ribeiro, RÔmulo Pereira (author);Carvalho, Katherine Athayde Teixeira de (author);Cardoso, Marco André (author);Pontarolo, Roberto (author)

Book ID
125827932
Publisher
Elsevier
Year
2014
Tongue
English
Weight
500 KB
Volume
967
Category
Article
ISSN
1873-376X

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✍ Isabela Costa César; Ricardo Martins Duarte Byrro; Fabiana Fernandes de Santana 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 381 KB 👁 1 views

A sensitive and fast high-performance liquid chromatography-electrospray ionization-MS/MS method for the simultaneous quantitation of levodopa and carbidopa in human plasma was developed and validated. A simple protein precipitation step with perchloric acid was used for the cleanup of plasma, and m