A conformationally constrained analogue of the paclitaxel side-chain was synthesised in an enantioselective way from ethyl IH-indene-2-carboxylate. Coupling with 7-triethylsilylbaccatin III and deprotection afforded 2',2"-methylenepaclitaxel, a novel analogue of the natural product retaining antican
✦ LIBER ✦
A New Conformationally Restricted Mimetic of Dipeptide EG – Synthesis of an Analogue of FEG
✍ Scribed by Roberta Galeazzi; Gianluca Martelli; Eleonora Marcucci; Giovanna Mobbili; Desiré Natali; Mario Orena; Samuele Rinaldi
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 185 KB
- Volume
- 2007
- Category
- Article
- ISSN
- 1434-193X
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