A New and Practical Synthesis of α-Amino Acids from Alkenyl Boronic Acids
✍ Scribed by Petasis, Nicos A.; Zavialov, Ilia A.
- Book ID
- 118234631
- Publisher
- American Chemical Society
- Year
- 1997
- Tongue
- English
- Weight
- 156 KB
- Volume
- 119
- Category
- Article
- ISSN
- 0002-7863
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Simple amino acids (1) can be converted in fair to good yield into hydrazino acids (3) of like configuration by using KOCI instead of NaOCl to promote the Shestakov rearrangement of the intermediate hydantoic acids (2). It was shown fifteen years ago by Karady et al.,' and later by Custafsson,' that
Aryl and heteroaryl boronic acids react with the adducts of amines and glyoxylic acid to give the corresponding o~-aryl and a-heteroaryl glycine derivatives. Several examples of this reaction with m-and p-substituted aryl boronic acids as well as 3-thienyl, 2-thienyl, 2-furyl, 2-benzo[b]furyl and 2-