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A new and improved synthesis of a potential antitumour 7h-pyrido[4,3-c ]carbazole analog.

✍ Scribed by Pascale Léon; Christiane Garbay-Jaureguiberry; Jean-Bernard Le Pecq; Bernard P. Roques

Book ID
108382604
Publisher
Elsevier Science
Year
1985
Tongue
French
Weight
238 KB
Volume
26
Category
Article
ISSN
0040-4039

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A theoretical investigation of the inter
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✍ Rachid Maroun; Nohad Gresh 📂 Article 📅 1989 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 832 KB

Theoretical computations are performed of the intercalative binding to a model d(CpC), minihelix of 7-H pyridd4.3C]carbazole, the precursor of the antitumor bisintercalating drug ditercalinium. The conformations of the intercalation site are generated by the AGNAS procedure (algorithm to generate nu