A CONVENIENT ROUTE FOR THE SYNTHESIS OFCIS-1-SUBSTITUTED 1,2,3,4,4a,5,11,11a-OCTAHYDRO-6H-PYRIDO[3,2-b]CARBAZOLES AND 4-SUBSTITUTED 1,2,3,4,4a,5,6,11c-OCTAHYDRO-7H-PYRIDO[2,3-c] CARBAZOLES AS POTENT DOPAMINE AGONISTS
โ Scribed by Keshav K. Awasthis; Ruchika Chakrabarty; Anil K. Saxena
- Publisher
- Springer-Verlag
- Year
- 2004
- Tongue
- English
- Weight
- 567 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1054-2523
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The molecule of the title compound, C~26~H~30~N~2~O~4~S, adopts a folded conformation, with the sulfonyl-bound benzene ring lying over the pyridinone ring [centroid-to-centroid distance = 3.893โ (1)โ ร ], forming a dihedral angle of 23.87โ (5)ยฐ. The pyrrolidine ring adopts a twist conformation and the d
The asymmetric unit of the title compound, C 26 H 30 N 2 O 4 S, consists of two independent molecules, A and B, with similar conformations. In both molecules, the pyrrolidine and dihydropyran rings adopt envelope conformations, and are trans-fused; the tosyl group is attached to the pyrrolidine ring
The geminal coupling constant C-8.0 Hz) for the N-CH2-0 protons in hexahydro-l&3!-pyrido [1,2-cl[1,3loxazine (1)' when compared with the corresponding n.m.r. parameter in cis-8,12a, -
The title compound, C~22~H~29~NO~4~S, crystallizes with three independent molecules, __A__, __B__ and __C__, in the asymmetric unit. Each of the three independent molecules adopts a folded conformation, with the phenylsulfonyl group lying over the pyranocyclohexanone ring system, and with the pyrrol