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A new and general procedure for the preparation of deoxynucleoside phosphoramidites

✍ Scribed by Jean-Louis Fourrey; Jeannette Varenne

Publisher
Elsevier Science
Year
1983
Tongue
French
Weight
216 KB
Volume
24
Category
Article
ISSN
0040-4039

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πŸ“œ SIMILAR VOLUMES

Improved procedure for the preparation o
Improved procedure for the preparation of deoxynucleoside phosphoramidites: Arylphosphoramidites as new convenient intermediates for oligodeoxynucleotide synthesis
✍ Jean-Louis Fourrey; Jeannette Varenne πŸ“‚ Article πŸ“… 1984 πŸ› Elsevier Science 🌐 French βš– 244 KB

A simplified procedure for the preparation of deoxynucleoside methyl-and arylphosphoramidites is described. Both types of phosphoramidites can be conveniently activated by N-methylaniline trifluoracetate for their use in oligodeoxynucleotide synthesis.

Deoxynucleoside phosphoramiditesβ€”A new c
Deoxynucleoside phosphoramiditesβ€”A new class of key intermediates for deoxypolynucleotide synthesis
✍ S.L. Beaucage; M.H. Caruthers πŸ“‚ Article πŸ“… 1981 πŸ› Elsevier Science 🌐 French βš– 302 KB

The development of a new class of nucleoside phosphites is described. These compounds are stable to normal laboratory conditions, are activated by mild acid treatment, and are observed to react essentially quantitatively with protected nucleosides. A recent, key innovation in oligonucleotide synthes