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A simple and efficient preparation of deoxynucleoside phosphoramidites in situ

✍ Scribed by Serge L. Beaucage


Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
281 KB
Volume
25
Category
Article
ISSN
0040-4039

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πŸ“œ SIMILAR VOLUMES


Nucleosides and Nucleotides. Part 17. A
✍ Silvio Bernardini; Felix Waldmeier; Christoph Tamm πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 German βš– 415 KB

## Abstract A simple method for the preparation of fully protected 2′‐deoxynucleoside‐3′‐phosphates is described. The main step, phosphorylation of partially protected deoxynucleosides, is performed with the monofunctional reagent __p__‐chlorophenyl (2‐cyanoethyl) phosphochloridate^3^) (**2**) in d