A molecular graphics study on structure-action relationships of calcium-antagonistic and agonistic 1,4-dihydropyridines
✍ Scribed by H. -D. Höltje; S. Marrer
- Book ID
- 105276470
- Publisher
- Springer Netherlands
- Year
- 1987
- Tongue
- English
- Weight
- 963 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0920-654X
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📜 SIMILAR VOLUMES
A group of methyl 1,4-dihydro-2,6-dimethyl-4-(2-, 3-or 4-NHOH; 3-or 4-N=O)-phenyl-5-pyridinecarboxylates possessing a C-3 CO 2 Me or NO 2 substituent [compounds 58, 1012, below] were synthesized by reduction of the C-4 nitrophenyl precursors [14] to the corresponding phenylhydroxylamine [58] derivat
4-Aryl and 4-methyl substituted Hantzsch-type 1,4-dihydropyridines having a chirat sulfinyl group as an electron-withdrawing group were successfully synthesized in an optically active form from [~-ketosulfoxides via two routes. The relationship between calcium channel antagonist activity and the str
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