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Qualitative and Quantitative Structure-Activity Relationships for Calcium Channel Modulating 1,4-Dihydropyridine Derivatives: A Hypothetical Molecular Receptor Model

✍ Scribed by Höltje, Hans-Dieter ;Marrer, Stephan


Book ID
112185267
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
464 KB
Volume
7
Category
Article
ISSN
1611-020X

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Quantitative structure-activity relation
✍ Anderson Coser Gaudio; Andrejus Korolkovas; Yuji Takahata 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 729 KB

A quantum chemical (AM1) combined with a classical study of structure-activity relationships for 1,4-dihydropyridines (nifedipine analogues) was performed. The biological data were taken from the literature. The quantum chemical parameters tested were energies of HOMO and LUMO, dipole moment (total