A Modified Sandmeyer Methodology and the Synthesis of (±)-Convolutamydine A. -A modified Sandmeyer methodology (lower temperature and addition of ethanol) is found to be useful for the high yield synthesis of α-isonitrosoacetanilides (III). Derivative (IIIc) is readily converted to (±)-convolutamyd
A modified Sandmeyer methodology and the synthesis of (±)-convolutamydine A
✍ Scribed by Simon J. Garden; JoséC. Torres; Alexandre A. Ferreira; Rosangela B. Silva; Angelo C. Pinto
- Book ID
- 104256513
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 224 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
t:)-Convohtamydine A (5) has been prepared by a concise synthesis from 3,5-dibromoaniline using a modified Sandmeyer methodology. The modified Sandmeyer methodology has also been found to be beneficial for the synthesis of other et-isonitrosoagetanilides. The 4,6-dibromobydroxyoxindole nucleus was further confirmed by comparison with the isomeric 5,7-dibromohydroxyoxindole.
📜 SIMILAR VOLUMES
EASTMAN KODAK COMPANY NOTES. III necessary to effect absorption of 8o per cent. of the theoretical amount of hydrogen sulphide. Possibly the catalyst acts by inducing the formation of an active modification of acetic anhydride. Acetyl chloride alone, or acetic anhydride alone, does not react with hy