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A modified pharmacokinetic model for platinum disposition in ovarian cancer patients receiving cisplatin

✍ Scribed by H. Griffiths; M. D. Shelley; R. G. Fish

Publisher
Springer
Year
1987
Tongue
English
Weight
546 KB
Volume
33
Category
Article
ISSN
0031-6970

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## Background and Objectives: We assessed the role of salvage chemotherapy with topotecan and cisplatin in patients with platinum-and paclitaxel-resistant advanced and recurrent ovarian or primary peritoneal cancer, based on the reported in vivo and in vitro synergism between these two drugs. Meth