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A Modified Approach to 2-( N -Aryl)-1,3-oxazoles: Application to the Synthesis of the IMPDH Inhibitor BMS-337197 and Analogues

✍ Scribed by Dhar, T. G. Murali; Guo, Junqing; Shen, Zhongqi; Pitts, William J.; Gu, Henry H.; Chen, Bang-Chi; Zhao, Rulin; Bednarz, Mark S.; Iwanowicz, Edwin J.


Book ID
126029832
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
50 KB
Volume
4
Category
Article
ISSN
1523-7060

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ChemInform Abstract: Palladium(II)-Catal
✍ Andreas Palmgren; Anna L. E. Larsson; Jan-E. Baeckvall; Paul Helquist πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 37 KB πŸ‘ 1 views

Palladium(II)-Catalyzed 1,4-Oxidation of 2-Aryl-1,3-cyclohexadienes. Application to the Synthesis of (Β±)-Epibatidine and Analogues. -1,4-Chloroacetoxylation of arenes (I) in the presence of palladium(II) catalyst gives cis-cyclohexenes (III) with high regio-and stereoselectivity. These products are