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A Modified Approach to 2-(N-Aryl)-1,3-oxazoles: Application to the Synthesis of the IMPDH Inhibitor BMS-337197 and Analogues.

✍ Scribed by T. G. Murali Dhar; Junqing Guo; Zhongqi Shen; William J. Pitts; Henry H. Gu; Bang-Chi Chen; Rulin Zhao; Mark S. Bednarz; Edwin J. Iwanowicz


Book ID
101933463
Publisher
John Wiley and Sons
Year
2010
Weight
37 KB
Volume
33
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


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ChemInform Abstract: Palladium(II)-Catal
✍ Andreas Palmgren; Anna L. E. Larsson; Jan-E. Baeckvall; Paul Helquist πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 37 KB πŸ‘ 1 views

Palladium(II)-Catalyzed 1,4-Oxidation of 2-Aryl-1,3-cyclohexadienes. Application to the Synthesis of (Β±)-Epibatidine and Analogues. -1,4-Chloroacetoxylation of arenes (I) in the presence of palladium(II) catalyst gives cis-cyclohexenes (III) with high regio-and stereoselectivity. These products are