Iron loaded transferrin (holotransferrin) was used for enrichment of fetal cells from peripheral blood of pregnant women. Cord blood samples were used to evaluate enrichment efficacy of single and double MACS separations. Blood samples were obtained from 10 pregnant women prior to chorion villus sam
A Model System Using Fetal Hemoglobin to Distinguish Fetal Cells Enriched from Maternal Blood
β Scribed by VICKI M. PARK; RALPH R. BRAVO; JAMES O. PRICE; JOE LEIGH SIMPSON; SHERMAN ELIAS
- Book ID
- 119871276
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 157 KB
- Volume
- 731
- Category
- Article
- ISSN
- 0890-6564
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In this study we evaluated the performance of a system for the enrichment, identification and analysis of fetal cells in maternal peripheral blood. Blood samples were collected from women after chorionic villus sampling and enriched for the presence of nucleated erythrocytes using a three-step proc
## To the Editor: Fetal nucleated erythrocytes circulating in maternal blood are a potential source of fetal DNA for noninvasive prenatal genetic diagnoses. Nucleated red blood cells (NRBCs) have several advantages over fetal lymphocytes, granulocytes, or trophoblasts. They are nucleated, and thus