A model for the resistance of tumor cells to cancer chemotherapeutic agents
β Scribed by A.J. Coldman; J.H. Goldie
- Book ID
- 116028972
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 894 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0025-5564
No coin nor oath required. For personal study only.
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## Abstract The mechanisms whereby malignant cells become biochemically resistant to antiβcancer drugs are surveyed, with emphasis on human tumors. Methoβtrexate is used as a model to illustrate the mechanisms of resistance that can occur, and how cells can increase their production of dihyrofolate
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