𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A mild and stereoselective synthesis of β-phosphonylacrylates

✍ Scribed by Kamyar Afarinkia; Marc Evans; Jocelyn C.H. Graham; Gorka Jimenez-Bueno

Book ID
104258493
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
169 KB
Volume
39
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

The addition of trimethylsilyloxy phosphorus (Ill) derivatives, generated in situ, to ct-haloacrylates and acryiordtriles at room temperature provides a mild, general and stereoselective route to 13-phosphonoacrylates.

📜 SIMILAR VOLUMES

Stereoselective synthesis of β-lactams
Stereoselective synthesis of β-lactams
✍ Alan D. Brown; Ernest W. Colvin 📂 Article 📅 1991 🏛 Elsevier Science 🌐 French ⚖ 127 KB

An efficient method for the preparation of chiral cis-3,4-disubstituted 8-1actams, based on reaction between imines from homochiral protected lactaldehydes and furfurylamine and phenyl dichlorophosphate activated carboxylic acid derivatives, is reported.

Stereoselective synthesis of β-hydroxycy
Stereoselective synthesis of β-hydroxycyclohexanones
✍ Alistair P. Rutherford; Cameron S. Gibb; Richard C. Hartley 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 220 KB

We have developed a stereoselective route to 13-hydroxycyclohexanones using the aldol reaction, the Takai alkylidenation, a novel anionic oxy-Cope rearrangement of acyclic enol ethers and an intramolecular aldol reaction. The stereoselectivity of the acid-induced, 6-(enolendo)-exo-trig, intramolecul