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A microwave synthesis of the cis and trans isomers of 3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one: The influence of solvent and power output on the diastereoselectivity

✍ Scribed by Juan A. Vega; Sénida Cueto; Andrés Ramos; Juan J. Vaquero; JoséL. García-Navio; Julio Alvarez-Builla; Jesus Ezquerra


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
240 KB
Volume
37
Category
Article
ISSN
0040-4039

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📜 SIMILAR VOLUMES


Asymmetric Synthesis of the cis- and tra
✍ Emmanuel Couché; Abdellatif Fkyerat; Raffaele Tabacchi 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 German ⚖ 165 KB

## Abstract A short and efficient protocol for the asymmetric synthesis of __cis__‐ and __trans__‐3,4‐dihydro‐2,4,8‐trihydroxynaphthalen‐1(2__H__)‐one (**1** and **2**, resp.) is described, with a phthalide annulation as the key step. Introduction of a OH substituent at position 2 was performed by