A method has been developed for the gas chromatographic analysis of lipoic acid in biological samples. The lipoic acid is released from the samples by acid hydrolysis in the presence of the internal standatds 1,2-dithiolane-3-butyric acid and/or 1,2-dithiolane-3caproic acid. After hydrolysis, the li
A method for the gas-chromatographic analysis of N-acetylaspartic acid in brain
✍ Scribed by F. Marcucci; E. Mussini
- Publisher
- Elsevier Science
- Year
- 1966
- Tongue
- English
- Weight
- 319 KB
- Volume
- 25
- Category
- Article
- ISSN
- 1873-3778
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## ABSTRACT The concentration of brain __N__‐acetylaspartic acid (NAA) in mice was determined by high‐performance liquid chromatography (HPLC) using fluorescence detection after pre‐column derivatization with 4‐__N__,__N__‐dimethylaminosulfonyl‐7‐__N__‐(2‐aminoethyl)amino‐2,1,3‐benzoxadiazole (DBD‐
An ion-pairing high-performance liquid chromatographic method for the determination of N-acetylaspartate and N-acetylglutamate using a C-18 column and a UV detection at 210 nm wavelength, by means of a diode array detector, is presented. A buffer containing 2.8 mM tetrabutylammonium hydroxide, 25 mM