## Abstract p‐Toluic acid‐ring‐^14^C was synthesized by the Friedel‐Crafts p‐carbamylation of toluene‐ring‐^14^C with N,N‐disubstituted carbamyl chloride and subsequent hydrolysis. The radiochemical yield was 61%. An attempt was made to apply this method for the synthesis of benzoic acid‐ring‐^14^C
A method for synthesis of 14C-labelled styrene
✍ Scribed by Andrzej Majcherczyk; Annette Braun-Lüllemann; Aloys Hüttermann
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- French
- Weight
- 388 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
Abstract
Side‐chain and ring ^14^C‐labelled styrene were synthesised from labelled benzene and acetaldehyde via bromobenzene, Grignard‐reagent and 1‐phenylethanol. Uniformly ^14^C‐labelled styrene can be also prepared using this method. By‐products were identified and the purity of products was determed by GC‐MS.
📜 SIMILAR VOLUMES
14C-Labelled satigrel, or 4-cyano-5-(4'-methoxy tring-U-14CI phenyl)-5-(4"methoxyphenyl)-4-pentenoic acid was synthesized for drug metabolism and pharmacokinetic studies using 4,4'-diniethoxy [ring-U-W ] benzophenone as the starting material. The radiochemical yield was 10.0%. The specific radioacti
The synthesis of 14C-labelled crotamiton, which is a fungicide, an insecticide as well as a scabicide is described. Starting from 2-bromonitrobenzene and Cu14CN, 2-toluidine, labelled with 14C at the methyl group was prepared by the following sequence of reactions : N O ~-C ~H L + -~~C O O H
## Abstract [^14^C]Aminoguanidine was synthesized by the reaction of hydrazine sulphate with barium [^14^C]cyanamide in a one‐step synthesis, and conveniently isolated by crystallization as the bicarbonate salt. The yield was 32%.
## Abstract ^14^C‐labelled (+)‐limonene was conveniently prepared by the Wittig reaction of (+)‐1‐methyl‐4‐acetylcyclohexene with methyl‐^14^C‐triphenylphosphonium iodide.