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A membrane-targeting signal in the amino terminus of the neuronal protein GAP-43

โœ Scribed by Zuber, Mauricio X.; Strittmatter, Stephen M.; Fishman, Mark C.


Book ID
109761228
Publisher
Nature Publishing Group
Year
1989
Tongue
English
Weight
745 KB
Volume
341
Category
Article
ISSN
0028-0836

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A combined assay to measure neurite outgrowth and B-50/GAP-43 levels in PC12 cells is reported. During NGF-induced neuritogenesis, B-50/GAP-43 expression was monitored by enzyme-linked immunosorbent assay (ELISA). Neurite outgrowth was quantified at the same time by the use of video image analysis.