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A mathematical model of the P-glycoprotein pump as a mediator of multidrug resistance

โœ Scribed by Seth Michelson; Doris Slate

Book ID
112754274
Publisher
Springer
Year
1992
Tongue
English
Weight
770 KB
Volume
54
Category
Article
ISSN
1522-9602

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๐Ÿ“œ SIMILAR VOLUMES

A mathematical model of the P-glycoprote
A mathematical model of the P-glycoprotein pump as a mediator of multidrug resistance
โœ Seth Michelson; Doris Slate ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer ๐ŸŒ English โš– 788 KB

Cells displaying the classic multidrug resistant (MDR) phenotype possess a transmembrane protein (p170 or P-glycoprotein) which can actively extrude cytotoxic agents from the cytoplasm. A mathematical model of this drug efflux pump has been developed. Outward transport is modeled as a facilitated di

The Biochemistry of P-Glycoprotein-Media
The Biochemistry of P-Glycoprotein-Mediated Multidrug Resistance
โœ Endicott, J A; Ling, V ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Annual Reviews ๐ŸŒ English โš– 897 KB

acetate; OAG, I-oleoyl 2-acetylglycerol; P(BtO)" phorhol 12, 13-dihutyrate; NASV, N-(p-azido [3-'25 Ijsalicyl)-N' -(J3-aminoethyl)vindesine; NABV, N-(p-azido-[3 ,5-3 Hjbenzoyl)-N' -(13aminoethyl)vindesine; OM, double minutes; HSR, homogeneously staining region.